Blood centers should implement alternate eligibility criteria or additional safety measures to protect teenage donors from iron depletion. Progression to hemoglobin deferral was twice as likely in 16- to 18-year-old versus 19- to 49-year-old females.Īge 16 to 18 years-old is an independent risk factor for iron deficiency in blood donors at any donation frequency. Adjusted odds for ferritin less than 12 ng/mL were 2.1 to 2.8 times greater in 16- to 18-year-olds than in 19- to 49-year-olds, and for ferritin less than 26 ng/mL were 3.3- to 4.7-fold higher in 16- to 18-year-olds. At enrollment, prevalence of ferritin less than 12 ng/mL in teenagers was 1% in males and 18% in females making their first blood donation, and 8% in males and 33% in females with prior donations. Multivariable repeated-measures logistic regression models evaluated the role of age and other demographic/donation factors.įerritin was measured from 4265 enrollment donations September to November 20 follow-up donations through May 2016. Plasma ferritin testing was performed with ferritin less than 12 ng/mL as our primary measure of iron depletion and ferritin less than 26 ng/mL a secondary measure. Successful, age-eligible donors were enrolled from high school blood drives at two large US blood centers. Study objectives were to determine the prevalence of iron depletion in 16- to 18-year-old donors and whether their risk for iron depletion was greater than adult donors. Mitigating iron depletion in these donors is important because they continue to undergo physical and neurocognitive development.

The main focus is on fixing, improving and balancing the game and expanding it with more gameplay mechanics, as well as to make the game more historical and realistic by adding more major and important historical events and nations in a way that it doesn't become too bloated and railroaded, as it also focuses. It's based on NNM and includes various reworked elements from other mods or minimods such as Vickymod, PDM etc.

High school students 16 to 18 years-old contribute 10% of the US blood supply. Blood and Iron is a major overhaul mod for Victoria 2: Heart of Darkness.

Victoria 2 blood and iron